Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-001674 |
CAS: 178101-88-7 |
Molecular Formula: C5[13C]H8O6 |
Molecular Weight: 177.12 |
Chemical Structure |
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Description | L-Ascorbic acid-1-[13C] is the labelled analogue of Vitamin C. Vitamin C is a naturally occurring organic compound with antioxidant properties. |
Synonyms | L-Threoascorbic acid-1-13C; L-Ascorbic acid-1-13C; L-[1-13C]ascorbic acid; [1-13C]vitamin C; Vitamin C-1-13C; L-Ascorbic Acid-1-13C |
IUPAC Name | (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-(5-13C)2H-furan-5-one |
Related CAS | 50-81-7 (unlabelled) |
Canonical SMILES | C(C(C1C(=C(C(=O)O1)O)O)O)O |
InChI | InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1/i6+1 |
InChI Key | CIWBSHSKHKDKBQ-HYAXHRHPSA-N |
Melting Point | 193 °C (dec.) |
Purity | 99% (CP); 99% atom 13C |
Solubility | Slightly soluble in DMSO, Methanol (Heated) |
Appearance | Off-white to Pale Beige Solid |
Storage | −20 °C under inert atmosphere |
L-Ascorbic acid-1-[13C], a stable isotope-labeled compound, finds wide application in scientific research. Here are the key uses of L-Ascorbic acid-1-[13C]:
Metabolic Flux Analysis: In the intricate realm of metabolic flux analysis, L-Ascorbic acid-1-[13C] serves as a powerful tool to trace the dynamic movement and transformation of ascorbic acid within biological systems. By integrating this labeled compound into metabolic investigations, researchers glean precise insights into ascorbic acid utilization, absorption, and biosynthesis. These data offer a nuanced understanding of cellular metabolism and illuminate the multifaceted roles of ascorbic acid across diverse metabolic pathways.
Nutritional Research: Delving into the depths of nutritional research, L-Ascorbic acid-1-[13C] plays a pivotal role in unraveling the intricacies of vitamin C bioavailability and metabolism in both humans and animals. By leveraging this labeled compound, scientists can meticulously quantify absorption rates, distribution patterns, and excretion dynamics of vitamin C with heightened accuracy. These revelations form the bedrock for crafting tailored dietary guidelines and optimizing strategies for vitamin C supplementation, paving the way for targeted nutritional interventions.
Pharmacokinetics: Embarking on the frontier of pharmacokinetic exploration, L-Ascorbic acid-1-[13C] emerges as a linchpin in evaluating the pharmacodynamic profile of vitamin C post-administration. This entails a comprehensive analysis of absorption kinetics, distribution dynamics, metabolic fate, and excretion patterns of vitamin C encapsulated within the realm of absorption, distribution, metabolism, and excretion (ADME) studies. Such insights are instrumental in sculpting effective dosing regimens and unraveling the therapeutic panorama of vitamin C-based interventions, heralding a new era in personalized medicine.
Biochemical Pathway Elucidation: Into the maze of biochemical pathway elucidation strides L-Ascorbic acid-1-[13C], offering researchers a lens to dissect the intricate dance of ascorbic acid within cellular processes. By meticulously tracking the journey of labeled carbon into various metabolites, scientists unravel the tapestry of intermediates and enzymes orchestrating these pathways, shedding light on the biochemical symphony conducted by ascorbic acid. These revelations deepen our understanding of the complex roles played by ascorbic acid in cellular functions, unveiling its profound impact on overall health and well-being.
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