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L-Ascorbic acid-1-[13C]

General Information
Catalog: BLP-001674
CAS: 178101-88-7
Molecular Formula: C5[13C]H8O6
Molecular Weight: 177.12
Chemical Structure
L-Ascorbic acid-1-[13C]
Description L-Ascorbic acid-1-[13C] is the labelled analogue of Vitamin C. Vitamin C is a naturally occurring organic compound with antioxidant properties.
Synonyms L-Threoascorbic acid-1-13C; L-Ascorbic acid-1-13C; L-[1-13C]ascorbic acid; [1-13C]vitamin C; Vitamin C-1-13C; L-Ascorbic Acid-1-13C
IUPAC Name (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-(5-13C)2H-furan-5-one
Related CAS 50-81-7 (unlabelled)
Canonical SMILES C(C(C1C(=C(C(=O)O1)O)O)O)O
InChI InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1/i6+1
InChI Key CIWBSHSKHKDKBQ-HYAXHRHPSA-N
Melting Point 193 °C (dec.)
Purity 99% (CP); 99% atom 13C
Solubility Slightly soluble in DMSO, Methanol (Heated)
Appearance Off-white to Pale Beige Solid
Storage −20 °C under inert atmosphere

L-Ascorbic acid-1-[13C], a stable isotope-labeled compound, finds wide application in scientific research. Here are the key uses of L-Ascorbic acid-1-[13C]:

Metabolic Flux Analysis: In the intricate realm of metabolic flux analysis, L-Ascorbic acid-1-[13C] serves as a powerful tool to trace the dynamic movement and transformation of ascorbic acid within biological systems. By integrating this labeled compound into metabolic investigations, researchers glean precise insights into ascorbic acid utilization, absorption, and biosynthesis. These data offer a nuanced understanding of cellular metabolism and illuminate the multifaceted roles of ascorbic acid across diverse metabolic pathways.

Nutritional Research: Delving into the depths of nutritional research, L-Ascorbic acid-1-[13C] plays a pivotal role in unraveling the intricacies of vitamin C bioavailability and metabolism in both humans and animals. By leveraging this labeled compound, scientists can meticulously quantify absorption rates, distribution patterns, and excretion dynamics of vitamin C with heightened accuracy. These revelations form the bedrock for crafting tailored dietary guidelines and optimizing strategies for vitamin C supplementation, paving the way for targeted nutritional interventions.

Pharmacokinetics: Embarking on the frontier of pharmacokinetic exploration, L-Ascorbic acid-1-[13C] emerges as a linchpin in evaluating the pharmacodynamic profile of vitamin C post-administration. This entails a comprehensive analysis of absorption kinetics, distribution dynamics, metabolic fate, and excretion patterns of vitamin C encapsulated within the realm of absorption, distribution, metabolism, and excretion (ADME) studies. Such insights are instrumental in sculpting effective dosing regimens and unraveling the therapeutic panorama of vitamin C-based interventions, heralding a new era in personalized medicine.

Biochemical Pathway Elucidation: Into the maze of biochemical pathway elucidation strides L-Ascorbic acid-1-[13C], offering researchers a lens to dissect the intricate dance of ascorbic acid within cellular processes. By meticulously tracking the journey of labeled carbon into various metabolites, scientists unravel the tapestry of intermediates and enzymes orchestrating these pathways, shedding light on the biochemical symphony conducted by ascorbic acid. These revelations deepen our understanding of the complex roles played by ascorbic acid in cellular functions, unveiling its profound impact on overall health and well-being.

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