L-Asparagine-[1-13C]

L-Asparagine-[1-13C], a stable isotope-labeled amino acid, finds diverse applications in research and diagnostics. Explore the following key applications of L-Asparagine-[1-13C] presented with elevated perplexity and burstiness:

Metabolic Flux Analysis: Delving into metabolic intricacies, L-Asparagine-[1-13C] is a pivotal tool in tracing carbon atom flow through metabolic pathways. By introducing this labeled amino acid into cells or organisms, researchers unravel the nuances of metabolic flux, discerning how cells allocate resources under varying conditions. This comprehensive approach sheds light on cellular metabolism, unveiling metabolic bottlenecks that may impact cellular function profoundly.

Protein Synthesis Studies: Embarking on the realm of protein research, L-Asparagine-[1-13C] emerges as a cornerstone for studying protein synthesis and turnover. Incorporating this isotope-labeled amino acid enables scientists to meticulously track the integration of asparagine into newly synthesized proteins. This investigation unveils the dynamic nature of protein synthesis, offering insights into the regulation of protein expression under both normal physiological conditions and pathological states, enriching our understanding of cellular processes.

Nuclear Magnetic Resonance (NMR) Spectroscopy: Navigating the realm of structural biology, L-Asparagine-[1-13C] is harnessed in NMR spectroscopy to unravel protein structure and function. The strategic 13C-labeling crystallizes into distinct signals that can be discerned and deconstructed, furnishing intricate details about the amino acid milieu within a protein. This profound analytical technique proves invaluable in deciphering the architecture of complex biomolecules and orchestrating the design of novel therapeutic agents, advancing the frontier of drug discovery.

Nutritional Research: In the domain of nutritional sciences, L-Asparagine-[1-13C] emerges as a vital asset for dissecting amino acid metabolism and its implications on overall health. Administering this labeled amino acid to subjects unveils a precise tracking of digestion, absorption, and integration of asparagine into bodily tissues. This investigative approach facilitates the evaluation of dietary protein quality and deepens our comprehension of metabolic responses to diverse nutritional interventions, paving the way for personalized dietary interventions tailored to individual needs.