L-Aspartic acid-[2,3,3-d3]

L-Aspartic acid-[2,3,3-d3], a deuterated variant of L-aspartic acid, finds predominant utility as a tracer in diverse scientific inquiries. Here are the key applications of L-Aspartic acid-[2,3,3-d3]:

Metabolic Flux Analysis: Employing L-Aspartic acid-[2,3,3-d3] in metabolic flux analysis allows for the exploration of intricate cellular metabolic pathways. By tracing the integration of this labeled compound, researchers delve into network dynamics and substrate utilization, unraveling the complexities of cellular metabolism and pinpointing potential targets for metabolic engineering.

Protein Turnover Studies: Within the realm of proteomics, L-Aspartic acid-[2,3,3-d3] emerges as a pivotal element for investigating protein turnover rates. Incorporated into proteins during synthesis, its presence can be discerned via mass spectrometry, enabling the assessment of protein degradation and synthesis rates. This aids in comprehending protein regulation across diverse physiological contexts, shedding light on dynamic cellular processes.

Neurotransmitter Research: Delving into the realm of neurotransmitter research, L-Aspartic acid-[2,3,3-d3] offers insights into the biosynthesis and metabolism of crucial neurotransmitters like glutamate in the brain. By following its metabolic journey, scientists probe the management and regulation of neurotransmitter pools, essential for unraveling the intricacies of neurological disorders and crafting precise therapeutic interventions.

Isotope Dilution Assays: Applied in isotope dilution assays, this compound facilitates the quantification of aspartic acid in biological samples. Through the addition of a known quantity of L-Aspartic acid-[2,3,3-d3], researchers can accurately gauge the concentration of the native compound using mass spectrometric methods. This precise approach plays a critical role in clinical diagnostics and nutritional investigations, providing valuable insights into biological processes.