L-Glutamic acid-[15N,d9]

L-Glutamic acid-[15N,d9], an amino acid labeled with stable isotopes, finds extensive use in scientific research. Here are key applications of L-Glutamic acid-[15N,d9], presented with high perplexity and burstiness:

Metabolic Tracing: Delving into metabolic intricacies, L-Glutamic acid-[15N,d9] is a cornerstone in tracing nitrogen flow within biological systems. Through incorporation of the labeled compound into organisms, researchers can meticulously monitor nitrogen's journey into proteins and other biomolecules, unraveling metabolic processes and shedding light on intricate pathways of transformation.

Protein Structure Analysis: In the realm of protein NMR studies, L-Glutamic acid-[15N,d9] emerges as a potent tool for delving into protein structure and dynamics. The introduction of isotopic labels facilitates the discernment of diverse nitrogen environments in protein backbone and side chains, aiding in unraveling protein conformation and intricate interactions with surrounding molecules.

Stable Isotope Labeling in Mass Spectrometry: Pioneering stable isotope labeling, L-Glutamic acid-[15N,d9] empowers mass spectrometry with enhanced capabilities for quantitative protein and peptide analysis. The incorporation of specific isotopes bestows a unique mass signature, enabling precise quantification of labeled molecules. This innovation proves invaluable in proteomics and analysis of complex biological samples, driving forward the frontiers of quantitative analytical techniques.

Neuroscience Research: Enriching neuroscience endeavors, L-Glutamic acid-[15N,d9] emerges as a pivotal player in exploring glutamate metabolism and neurotransmission. Glutamate, a crucial neurotransmitter in brain function, is scrutinized through labeled versions, unraveling its implications in synaptic function and neurophysiological processes. This exploration fuels deeper insights into neurological disorders and heralds potential breakthroughs in therapeutic interventions for brain-related afflictions.