CAS 159663-16-8 L-Glutamine-[1-13C] - Isotope / BOC Sciences

General Information
Catalog: BLP-009022
CAS: 159663-16-8
Molecular Formula: C4[13C]H10N2O3
Molecular Weight: 147.14

General Information

Catalog: BLP-009022

CAS: 159663-16-8

Molecular Formula: C4[13C]H10N2O3

Molecular Weight: 147.14

Chemical Structure

Description	L-Glutamine-[1-13C] is the labelled analogue of L-Glutamine. L-Glutamine is one of the 20 amino acids encoded by the standard genetic code. Ingredient of health care products.
Synonyms	L-Glutamine-1-13C
IUPAC Name	(2S)-2,5-diamino-5-oxo(1-13C)pentanoic acid
Related CAS	56-85-9 (unlabelled)
Isomeric SMILES	C(CC(=O)N)[C@@H]([13C](=O)O)N
Canonical SMILES	C(CC(=O)N)C(C(=O)O)N
InChI	InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i5+1
InChI Key	ZDXPYRJPNDTMRX-YTCQKPCCSA-N
Purity	98% by CP; 99% atom 13C
Storage	Store at 2-8°C

L-Glutamine-[1-13C], a compound enriched with stable isotopes, finds extensive use in a multitude of research and diagnostic realms. Here are the key applications of L-Glutamine-[1-13C]:

Metabolic Tracing: Delving into metabolic pathways, L-Glutamine-[1-13C] emerges as a pivotal tool for scrutinizing the intricate web of glutamine-driven metabolic processes. Through tracking the labeled carbon atoms, researchers embark on a journey to unveil the transformation of glutamine into diverse metabolites, shedding light on the convoluted metabolic fluxes governing cellular activities. This investigative approach bears significant relevance in the realm of cancer metabolism and diseases characterized by metabolic reprogramming, opening avenues for profound insights into cellular energetics.

NMR Spectroscopy: Unfolding the molecular tapestry, L-Glutamine-[1-13C] plays a crucial role in nuclear magnetic resonance (NMR) spectroscopy as a tracer, illuminating the structural intricacies and dynamic behaviors of biomolecules. By leveraging the carbon-13 label, researchers unlock enhanced spectral resolution, facilitating the dissection of complex molecular interactions vital for drug discovery and the structural elucidation of macromolecules. This application stands as an indispensable pillar in unraveling the mysteries of molecular architectures and biological recognition events.

Cell Culture Studies: Within the domain of cell culture exploration, L-Glutamine-[1-13C] serves as a cornerstone for unraveling the metabolic intricacies and nutrient utilization patterns of cultured cells. Introducing the labeled compound into the confines of the culture medium, researchers embark on a quest to decode how cells harness and interweave glutamine into diverse biochemical pathways, unraveling the cellular symphony of nutrient processing. This knowledge reservoir stands as a linchpin for optimizing cellular growth conditions and enhancing the efficiency of biologics production, underpinning the marriage of cell biology and metabolic engineering.