L-idose-[6-13C]

L-idose-[6-13C], a stable isotope-labeled sugar, serves as a unique tool with diverse applications in biochemical and biophysical research. Here are the key applications of L-idose-[6-13C]:

Metabolic Flux Analysis: Employing L-idose-[6-13C] for metabolic flux analysis allows researchers to unravel the intricate pathways of carbohydrate metabolism within cells. By integrating this labeled sugar into metabolic investigations, scientists can track the carbon flux across various metabolic pathways. This insight aids in deciphering cellular energy generation, biosynthesis processes, and metabolic abnormalities, shedding light on the dynamic nature of cellular metabolism.

NMR Spectroscopy: In the realm of Nuclear Magnetic Resonance (NMR) spectroscopy, L-idose-[6-13C] plays a pivotal role in facilitating detailed structural and dynamic examinations of carbohydrates and their molecular interactions. The incorporation of the 13C label enhances the resolution and sensitivity of NMR signals, enabling researchers to unveil the conformational intricacies and binding affinities of L-idose and its derivatives. This advanced characterization allows for a profound understanding of complex carbohydrate-based biomolecules and their functions within biological systems.

Glycoscience Research: Within the field of glycoscience, L-idose-[6-13C] serves as a valuable asset for exploring the biosynthesis and functions of glycosaminoglycans and other intricate carbohydrates. By leveraging labeled L-idose, researchers can delve into the enzymatic processes underlying these biosynthetic pathways, offering insights into the development of therapeutic interventions targeting carbohydrate-associated diseases like cancer and inflammatory conditions. This research contributes to the advancement of knowledge in glycoscience and potential treatment modalities for complex diseases.

Stable Isotope Labeling: Widely employed in stable isotope labeling experiments, L-idose-[6-13C] is instrumental in quantifying the integration of isotopes into biological macromolecules. This technique plays a critical role in mass spectrometry-based proteomics and metabolomics studies, where precision and accuracy in labeling are paramount. By enabling the identification and quantification of proteins and metabolites in complex biological samples, stable isotope labeling with L-idose-[6-13C] drives forward our understanding of cellular function and disease processes, offering a deeper insight into the intricate molecular landscape of biological systems.