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L-Leucine-[13C6,15N,d10]

General Information
Catalog: BLP-001678
Molecular Formula: [13C]6H3D10[15N]O2
Molecular Weight: 148.18
Chemical Structure
L-Leucine-[13C6,15N,d10]
Description L-Leucine-[13C6,15N,d10] is the labelled analogue of L-Leucine. L-Leucine is an essential branched-chain amino acid used in the biosynthesis of protein. It is obtained from dietary sources. Protein supplement in health care products.
Synonyms (S)-2-Amino-4-methylpentanoic acid-13C6,15N,2,3,4,4,5,5,5-d7,4-methyl-d3; L-Leucine-13C6,15N,2,3,3,4,5,5,5-d7,4-methyl-d3
IUPAC Name (2S)-2-(15N)azanyl-2,3,3,4,5,5,5-heptadeuterio-4-(trideuteriomethyl)(1,2,3,4-13C4)pentanoic acid
Related CAS 61-90-5 (unlabelled)
Canonical SMILES CC(C)CC(C(=O)O)N
InChI InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1D3,2D3,3+1D2,4+1D,5+1D,6+1,7+1
InChI Key ROHFNLRQFUQHCH-SWMPFDNYSA-N
Melting Point > 300 °C
Purity 95% (CP); 99% atom 13C; 98% atom 15N; 98% atom D

L-Leucine-[13C6,15N,d10], a stable isotope-labeled amino acid renowned for its distinctive labeling properties, finds widespread utility in bioscience research. Here are the key applications of L-Leucine-[13C6,15N,d10], infused with high levels of perplexity and burstiness

Metabolic Flux Analysis: Delving into metabolic intricacies, L-Leucine-[13C6,15N,d10] serves as a cornerstone for tracing cellular metabolic pathways and fluxes. By integrating this labeled leucine into cellular proteins, researchers can meticulously track its distribution and turnover through advanced mass spectrometry techniques. This approach sheds light on metabolic processes and elucidates the pivotal role of leucine in protein synthesis and energy metabolism

Protein Turnover Studies: Facilitating precise quantification, the labeled L-Leucine empowers researchers to gauge protein synthesis and degradation rates within living organisms. Administering L-Leucine-[13C6,15N,d10] to experimental subjects enables scientists to monitor the assimilation of the labeled amino acid into newly synthesized proteins. Such data is critical for unraveling protein dynamics, maintaining muscle protein equilibrium, and exploring the impacts of diverse conditions on protein metabolism

Nutritional Research: A cornerstone in nutritional inquiry, L-Leucine-[13C6,15N,d10] serves as a vital tool for exploring leucine metabolism and its implications for human health. Leveraging this labeled amino acid, researchers can investigate the utilization of dietary leucine by the body, shedding light on its effects on muscle development, recovery, and overall metabolic processes. This application is particularly significant for gauging the nutritional requirements of varied populations, encompassing athletes and individuals with metabolic disorders

Pharmaceutical Development: Within the realm of pharmaceutical innovation, L-Leucine-[13C6,15N,d10] emerges as a pivotal asset for studying drug metabolism and pharmacokinetics. By monitoring the journey of the labeled amino acid in the presence of pharmaceutical compounds, researchers unravel valuable insights into drug interactions and their impacts on amino acid metabolism. This knowledge aids in refining drug formulations, optimizing therapeutic outcomes, and comprehending their influence on protein synthesis and degradation pathways

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