L-Lysine-[6-13C] Dihydrochloride

L-Lysine-[6-13C] Dihydrochloride is a stable isotope-labeled amino acid used for various research and analytical purposes. Here are some key applications of L-Lysine-[6-13C] Dihydrochloride:

Metabolic Flux Analysis: L-Lysine-[6-13C] Dihydrochloride is extensively used in metabolic flux analysis to trace carbon flow within cellular pathways. By incorporating this labeled compound into biological systems, researchers can map out metabolic networks and understand how different pathways contribute to cellular function. This information is critical for metabolic engineering and optimizing production processes in biotechnology.

Proteomics Studies: In proteomics, L-Lysine-[6-13C] Dihydrochloride is utilized in mass spectrometry to accurately quantify proteins and their modifications. The isotopic labeling allows for differentiation between newly synthesized and pre-existing proteins, providing insights into protein turnover and synthesis rates. This technique is valuable for examining cellular responses to external stimuli and uncovering protein dynamics.

Nutritional Research: L-Lysine-[6-13C] Dihydrochloride can be used in nutritional studies to investigate lysine metabolism and its role in protein synthesis. By incorporating the labeled lysine into dietary interventions, researchers can assess lysine bioavailability and its impact on growth and development. This application is particularly important in understanding essential amino acid requirements and optimizing dietary formulations.

Pharmacokinetics: The use of L-Lysine-[6-13C] Dihydrochloride in pharmacokinetic studies helps in tracking lysine-containing drugs or supplements within the body. By monitoring the labeled amino acid, scientists can determine absorption, distribution, metabolism, and excretion profiles of lysine-related compounds. This provides essential information for dose optimization and improving therapeutic efficacy in clinical settings.