L-Ornithine-[4,4,5,5-d4] hydrochloride

L-Ornithine-[4,4,5,5-d4] hydrochloride is a stable isotope-labeled compound widely used in various biochemical and medical research applications. Here are some key applications of L-Ornithine-[4,4,5,5-d4] hydrochloride:

Metabolic Studies: L-Ornithine-[4,4,5,5-d4] hydrochloride is instrumental in studying metabolic pathways involving ornithine, such as the urea cycle. By tracing the labeled isotopes through metabolic processes, researchers can elucidate the dynamics and regulation of these pathways. This helps in understanding the metabolic disorders associated with ornithine deficiencies or dysregulations.

Protein Turnover Analysis: This labeled compound is utilized to study protein synthesis and degradation rates in cells and organisms. By incorporating L-Ornithine-[4,4,5,5-d4] into newly synthesized proteins, scientists can track protein turnover using mass spectrometry. This provides detailed insights into protein metabolism and homeostasis under various physiological conditions.

Pharmacokinetic Studies: L-Ornithine-[4,4,5,5-d4] hydrochloride can be used to investigate the pharmacokinetics and bioavailability of ornithine-based supplements or drugs. By administering the labeled compound and monitoring its distribution and clearance, researchers can optimize dosage forms and therapeutic regimens. This is crucial for developing effective clinical interventions and nutraceutical products.