L-Serine-[carboxyl-18O2]

L-Serine-[carboxyl-18O2], an isotopically labeled amino acid, holds specialized significance in research and diagnostics. Here are some key applications:

Metabolic Tracing: Delve into the intricate realm of metabolic tracing studies where L-Serine-[carboxyl-18O2] plays a pivotal role in unraveling metabolic pathways and fluxes. By integrating this labeled amino acid into cellular systems, researchers embark on a journey to trace the flow and transformations of compounds along diverse biochemical routes. This deep dive provides nuanced insights into cellular metabolism, aiding in the comprehension of metabolic disorders and the formulation of innovative therapeutic approaches.

Protein Synthesis Studies: Embark on a voyage through the fascinating domain of protein synthesis studies guided by the incorporation of L-Serine-[carboxyl-18O2] into proteins. This journey offers a window into the intricate processes of protein synthesis and turnover, shedding light on the dynamics of protein assembly and degradation. This exploration proves invaluable in the investigation of diseases characterized by abnormal protein synthesis, such as neurodegenerative disorders, offering a fresh perspective on disease mechanisms.

Mass Spectrometry: Enter the realm of mass spectrometry where L-Serine-[carboxyl-18O2] stands as a crucial standard for the quantitative analysis of amino acids and peptides. The distinctive isotopic label serves as an internal beacon, guiding researchers towards precise quantification and enhancing the accuracy of mass spectrometric data. This application serves as a cornerstone in diverse fields, including proteomics, metabolomics, and clinical diagnostics, revolutionizing the way we analyze complex biological samples.

Stable Isotope-Resolved Metabolomics (SIRM): Embark on a journey into the realm of Stable Isotope-Resolved Metabolomics (SIRM), where L-Serine-[carboxyl-18O2] serves as a beacon of discovery. Through the incorporation of stable isotopes into metabolic intermediates, this technique unveils intricate metabolic networks, offering detailed insights into metabolic activities under varying physiological and pathological conditions. SIRM emerges as a powerful tool for unraveling the complexities of cancer metabolism, metabolic disorders, and the impact of pharmaceutical interventions on metabolic pathways, transforming our understanding of disease processes.