Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009540 |
Molecular Formula: C10[13C]H12N2O2 |
Molecular Weight: 205.22 |
Chemical Structure |
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Description | L-Tryptophan-[indole-3-13C] is a 13C labelled L-Tryptophan, which is an essential amino acid and a precursor to both serotonin and melatonin. Serotonin is a neurotransmitter playing a role in regulating appetite, sleep, mood, and pain. |
Synonyms | H-Trp-OH-indole-3-13C; (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid-indole-3-13C |
Related CAS | 73-22-3 (unlabelled) |
InChI | InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1/i7+1 |
InChI Key | QIVBCDIJIAJPQS-WQVCYBKOSA-N |
Purity | 98% by CP; 95% atom 13C |
Appearance | White Solid |
L-Tryptophan-[indole-3-13C], a stable isotope-labeled amino acid with significant scientific implications, finds diverse applications. Here are the key applications explained with high perplexity and burstiness:
Nutritional Studies: Embarking on the journey of nutritional research, L-Tryptophan-[indole-3-13C] emerges as a guiding light in tracing the intricate metabolic pathways of tryptophan within the human body. Through meticulous monitoring of this isotope-labeled compound, researchers delve into the world of tryptophan absorption, conversion, and utilization with unparalleled precision. This detailed analysis unveils the multifaceted role of tryptophan in nutrition, shedding light on its nuanced impact on human health.
Protein Synthesis Research: Delving deeper into the realm of protein synthesis, the utilization of this labeled compound proves to be an invaluable asset. By seamlessly incorporating L-Tryptophan-[indole-3-13C] into proteins, scientists unlock the gateway to leveraging mass spectrometry for dissecting the intricate composition and dynamics of proteins. This cutting-edge technique serves as a powerful lens into the complex universe of protein structure, function, and adaptations in response to a myriad of environmental stimuli.
Neurotransmitter Research: Standing at the forefront of neurotransmitter investigations, L-Tryptophan-[indole-3-13C] emerges as a pivotal player in unraveling the enigmatic serotonin biosynthesis pathways. Given tryptophan's pivotal role as a precursor to serotonin, researchers harness the potential of this labeled compound to dissect the labyrinthine pathways and kinetics governing serotonin production in the brain. This deep dive into biochemical processes holds the key to unraveling the mysteries of mood disorders at a molecular level, paving the way for innovative therapeutic strategies.
Pharmacokinetics: Venturing into the realm of pharmacokinetic explorations, L-Tryptophan-[indole-3-13C] stands as a beacon of illumination in unraveling the intricate dynamics of absorption, distribution, metabolism, and excretion of tryptophan-based pharmaceuticals. Through meticulous tracking of this labeled compound, researchers gain unparalleled insights into the behavior of drugs derived from tryptophan within the human body. This reservoir of data not only informs the refinement of therapeutic approaches but also serves as the driving force behind the optimization of tryptophan-centric pharmaceutical interventions.
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