L-Tyrosine-[2-13C,15N]

L-Tyrosine-[2-13C,15N], a stable isotope-labeled amino acid utilized in various research applications in the biosciences, offers a multitude of uses. Here are key applications of L-Tyrosine-[2-13C,15N] presented with high perplexity and burstiness:

Metabolic Flux Analysis: Delving into metabolic flux analysis, researchers leverage L-Tyrosine-[2-13C,15N] to unravel the intricate pathways and rates at which cells metabolize nutrients. By integrating this labeled compound, scientists can meticulously trace the metabolic destiny of tyrosine, aiding in the elucidation of pathways such as neurotransmitter biosynthesis. This groundbreaking technique provides profound insights into cellular metabolism and aids in the comprehension of amino acid metabolism disorders, shedding light on crucial physiological processes.

Protein Structure Elucidation: In the realm of structural biology, L-Tyrosine-[2-13C,15N] assumes a pivotal role in NMR spectroscopy for probing protein structures. By introducing carbon-13 and nitrogen-15 isotopes into proteins, researchers gain intricate details about protein folding and dynamics, fostering a deeper understanding of protein functionality. This knowledge is paramount for unraveling the complexities of protein functions and serves as a cornerstone for drug discovery endeavors targeting specific protein entities, offering a glimpse into the intricate machinery of life.

Nutritional Studies: Infused with stable isotopes, L-Tyrosine-[2-13C,15N] is a cornerstone of nutritional research, enabling the evaluation of amino acid absorption and utilization in the human body. Researchers harness this compound to investigate how dietary choices impact tyrosine metabolism and how metabolic irregularities influence nutrient assimilation. This foundational work aids in the formulation of tailored nutritional guidelines and therapeutic interventions aimed at optimizing metabolic health, transcending traditional approaches to nutrition research.

Disease Mechanism Investigation: In the realm of medical inquiry, L-Tyrosine-[2-13C,15N] emerges as a potent tool for probing metabolic shifts linked to diseases ranging from cancer to neurodegenerative disorders. By tracing the metabolic journeys of tyrosine within disease models, researchers unveil alterations in metabolism that underpin disease progression. This invaluable data serves as a beacon for identifying potential disease biomarkers and therapeutic targets, offering a glimmer of hope in the quest for effective disease management strategies and personalized medicine.