L-Valine-N-Boc-[13C5,15N]

L-Valine-N-Boc-[13C5,15N], an isotopically labeled amino acid, finds wide-ranging applications in scientific research. Here are key applications of L-Valine-N-Boc-[13C5,15N] presented with high perplexity and burstiness:

NMR Spectroscopy: A cornerstone in Nuclear Magnetic Resonance (NMR) spectroscopy, this isotopically labeled compound plays a vital role in unraveling protein structures. By incorporating L-Valine-N-Boc-[13C5,15N] into proteins, researchers delve into intricate structural details at the atomic level. The distinct isotopic labels heighten the resolution and sensitivity of NMR experiments, facilitating precise mapping of protein folding and dynamic behaviors.

Metabolic Flux Analysis: In metabolic investigations, L-Valine-N-Boc-[13C5,15N] serves as a powerful tool for tracing amino acid metabolism pathways within living organisms. By introducing this labeled compound into metabolic networks, researchers quantify fluxes and conversions of valine, shedding light on cellular metabolic processes and unveiling potential targets for metabolic manipulation.

Proteomics Research: Valuable in quantitative proteomics, isotopically labeled valine enables accurate assessment of protein expression levels. By scrutinizing the integration of L-Valine-N-Boc-[13C5,15N] across different samples, scientists discern fluctuations in protein abundance across diverse conditions. This application is pivotal for delving into biological responses and uncovering indicative biomarkers.

Drug Development: In the realm of pharmaceutical innovation, L-Valine-N-Boc-[13C5,15N] plays a critical role in deciphering drug-protein interactions and pharmacokinetics. Employing this labeled valine in drug binding studies, researchers track binding sites and conformational alterations of target proteins. This knowledge is fundamental for crafting more potent and selective drugs with enhanced therapeutic efficacy.