L-Valine-[2-13C,15N]

L-Valine-[2-13C,15N], an isotopically labeled amino acid, finds diverse applications in research and analytics. Dive into the high perplexity and burstiness of the key applications:

Metabolic Flux Analysis: Delving into metabolic pathways, L-Valine-[2-13C,15N] becomes a pivotal player in metabolic flux analysis. By infusing it into growth media, scientists can meticulously track the isotopic integration into metabolic products. This unravels profound insights into cellular metabolism dynamics, paving the way for refined metabolic engineering strategies.

Proteomics: Unveiling protein dynamics and turnover rates, L-Valine-[2-13C,15N] takes center stage in proteomics exploration. Incorporation of this labeled amino acid into proteins sets the stage for detailed quantitative scrutiny through mass spectrometry. This data is paramount in unraveling the mysteries of protein synthesis, degradation, and intricate cellular regulation mechanisms.

NMR Spectroscopy: With its isotopic label, L-Valine-[2-13C,15N] emerges as a crucial asset in nuclear magnetic resonance (NMR) spectroscopy. Enhancing signal resolution and detection, this labeled amino acid aids in unraveling the structural complexities of proteins and intricate molecules. NMR studies harnessing this tool shed light on molecular interactions and fascinating conformational changes.

Pharmaceutical Research: Stepping into the realm of pharmaceutical exploration, L-Valine-[2-13C,15N] plays a vital role in scrutinizing drug metabolism and pharmacokinetics. Researchers trace the incorporation and dispersion of this labeled amino acid across various tissues, unveiling insights into the metabolic destiny and dynamics of therapeutic compounds. This knowledge fuels the development of safer and more efficacious therapeutic agents, shaping the future of pharmaceutical innovation.