Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-011925 |
CAS: 1219332-91-8 |
Molecular Formula: C8[13C]5H13N3O3 |
Molecular Weight: 264.22 |
Chemical Structure |
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Description | Lenalidomide is a labelled Lenalidomide. Lenalidomide is a cereblon binder, which induces ubiquitination and degradation of CK1a and transcription factors IKZF1, IKZF3 and SALL4 by E3 ubiquitin ligase. |
Synonyms | Lenalidomide 13C5; 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione-13C5 |
IUPAC Name | 3-(7-amino-3-oxo-1H-isoindol-2-yl)(2,3,4,5,6-13C5)azinane-2,6-dione |
Related CAS | 191732-72-6 (unlabelled) |
Isomeric SMILES | C1C2=C(C=CC=C2N)C(=O)N1[13CH]3[13CH2][13CH2][13C](=O)N[13C]3=O |
Canonical SMILES | C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N |
InChI | InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)/i4+1,5+1,10+1,11+1,12+1 |
InChI Key | GOTYRUGSSMKFNF-GSUYAWNGSA-N |
Melting Point | 248-250°C |
Purity | 95% atom 13C |
Solubility | Soluble in DMSO, Methanol |
Appearance | Pale Yellow to Light Yellow Solid |
Application | Labelled Lenalidomide (L328000). Immunomodulatory drug; analog of Thalidomide. |
Storage | Store at -20°C |
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