Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-012406 |
CAS: 1227162-34-6 |
Molecular Formula: C13H8D5N3O3 |
Molecular Weight: 264.29 |
Chemical Structure |
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Description | Lenalidomide-d5 is a deuterated form of Lenalidomide. Lenalidomide (CC-5013) is a derivative of Thalidomide and functions as an orally active immunomodulator. It acts through cereblon-mediated selective ubiquitination and degradation of IKZF1 and IKZF3 lymphocyte transcription factors, inhibiting the growth of mature B-cell lymphomas including multiple myeloma, and inducing interleukin-2 (IL-2) release from T cells. |
Synonyms | Lenalidomide D5 |
IUPAC Name | 3-(7-amino-3-oxo-1H-isoindol-2-yl)-3,4,4,5,5-pentadeuteriopiperidine-2,6-dione |
Related CAS | 191732-72-6 (unlabelled) |
Canonical SMILES | C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N |
InChI | InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)/i4D2,5D2,10D |
InChI Key | GOTYRUGSSMKFNF-QTQWIGFBSA-N |
Boiling Point | 614.0±55.0 °C at 760 mmHg |
Purity | 95% by HPLC; 95% atom D |
Density | 1.5±0.1 g/cm3 |
Solubility | DMSO: soluble; Methanol: soluble |
Storage | Store at -20°C |
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