Name: Lopinavir-[d8]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-015118

CAS: 1224729-35-4

Molecular Formula: C37H40D8N4O5

Molecular Weight: 636.85

Chemical Structure

Description	Lopinavir-[d8] is the labelled form of Lopinavir, which is a selective HIV protease inhibitor used as an antiretroviral medication.
Synonyms	Lopinavir D8; ABT 378-d8; Aluviran-d8; Koletra-d8; (αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-[1-(methyl-d3)ethyl-1,2,2,2-d4]-2-oxo-1(2H)-pyrimidineacetamide-α-d
IUPAC Name	(2S)-2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
Related CAS	192725-17-0 (unlabelled)
Canonical SMILES	[2H][C@@](C(=O)N[C@@H](CC1=CC=CC=C1)C[C@@H]([C@H](CC2=CC=CC=C2)NC(=O)COC3=C(C=CC=C3C)C)O)(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])N4CCCNC4=O
InChI	InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1/i1D3,2D3,25D,34D
InChI Key	KJHKTHWMRKYKJE-FQJAQOFRSA-N
Boiling Point	924.2±65.0 °C at 760 mmHg
Flash Point	512.7±34.3 °C
Purity	98% by CP; 98% atom D
Density	1.2±0.1 g/cm3
Solubility	Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance	Off-white to pale beige solid
Storage	Store at 2-8 °C