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Memantine-[d6] Hydrochloride

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General Information
Catalog: BLP-012434
CAS: 1189713-18-5
Molecular Formula: C12H16D6ClN
Molecular Weight: 221.89

Chemical Structure

Description	Memantine-[d6] Hydrochloride is the labelled salt of Memantine, which is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA receptors. It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6.
Synonyms	Memantine D6 Hydrochloride; 3,5-(Dimethyl-d6)tricyclo[3.3.1.13,7]decan-1-amine Hydrochloride; 3,5-(Dimethyl-d6)-1-adamantanamine; 1-Amino-3,5-(dimethyl-d6)adamantane Hydrochloride
IUPAC Name	(3R,5S)-3,5-bis(trideuteriomethyl)adamantan-1-amine;hydrochloride
Related CAS	41100-52-1 (unlabelled)
Canonical SMILES	CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
InChI	InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H/t9?,10-,11+,12?;/i1D3,2D3;
InChI Key	LDDHMLJTFXJGPI-XJAKYWJYSA-N
Melting Point	>270°C (dec.)
Purity	95% by HPLC; 95% atom D
Solubility	Soluble in DMSO, Methanol
Appearance	White to Off-white Solid
Storage	Store at -20°C, under inert atmosphere