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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Memantine-[d6] Hydrochloride

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General Information
Catalog: BLP-012434
CAS: 1189713-18-5
Molecular Formula: C12H16D6ClN
Molecular Weight: 221.89
Chemical Structure
Memantine-[d6] Hydrochloride
Description Memantine-[d6] Hydrochloride is the labelled salt of Memantine, which is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA receptors. It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6.
Synonyms Memantine D6 Hydrochloride; 3,5-(Dimethyl-d6)tricyclo[3.3.1.13,7]decan-1-amine Hydrochloride; 3,5-(Dimethyl-d6)-1-adamantanamine; 1-Amino-3,5-(dimethyl-d6)adamantane Hydrochloride
IUPAC Name (3R,5S)-3,5-bis(trideuteriomethyl)adamantan-1-amine;hydrochloride
Related CAS 41100-52-1 (unlabelled)
Canonical SMILES CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
InChI InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H/t9?,10-,11+,12?;/i1D3,2D3;
InChI Key LDDHMLJTFXJGPI-XJAKYWJYSA-N
Melting Point >270°C (dec.)
Purity 95% by HPLC; 95% atom D
Solubility Soluble in DMSO, Methanol
Appearance White to Off-white Solid
Storage Store at -20°C, under inert atmosphere
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