Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-012434 |
CAS: 1189713-18-5 |
Molecular Formula: C12H16D6ClN |
Molecular Weight: 221.89 |
Chemical Structure |
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Description | Memantine-[d6] Hydrochloride is the labelled salt of Memantine, which is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA receptors. It is also a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6. |
Synonyms | Memantine D6 Hydrochloride; 3,5-(Dimethyl-d6)tricyclo[3.3.1.13,7]decan-1-amine Hydrochloride; 3,5-(Dimethyl-d6)-1-adamantanamine; 1-Amino-3,5-(dimethyl-d6)adamantane Hydrochloride |
IUPAC Name | (3R,5S)-3,5-bis(trideuteriomethyl)adamantan-1-amine;hydrochloride |
Related CAS | 41100-52-1 (unlabelled) |
Canonical SMILES | CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl |
InChI | InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H/t9?,10-,11+,12?;/i1D3,2D3; |
InChI Key | LDDHMLJTFXJGPI-XJAKYWJYSA-N |
Melting Point | >270°C (dec.) |
Purity | 95% by HPLC; 95% atom D |
Solubility | Soluble in DMSO, Methanol |
Appearance | White to Off-white Solid |
Storage | Store at -20°C, under inert atmosphere |
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