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Mertansine-[13C,d3]

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Metabolic Research

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Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Mertansine-[13C,d3]

Name: Mertansine-[13C,d3]
Brand: BOC Sciences
Rating: 5 (1 reviews)

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General Information
Catalog: BLP-004684
Molecular Formula: C34[13C]H45D3ClN3O10S
Molecular Weight: 742.30

Chemical Structure

Description	Mertansine-[13C,d3] is the labelled analogue of Mertansine. Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP linker or SMCC linker to create an antibody-drug conjugate.
Synonyms	Mertansine 13CD3; N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine-13CD3; DM 1-13CD3; Maytansinoid DM 1-13CD3
IUPAC Name	(14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(3-mercaptopropanoyl)-N-(methyl-13C-d3)-L-alaninate
Related CAS	139504-50-0 (unlabelled)
Melting Point	>167°C (dec.)
Purity	≥98%; ≥99% atom 13C, ≥99% atom D
Solubility	Slightly soluble in Chloroform, Methanol
Appearance	White to Off-white Solid
Storage	Store at -20°C under inert atmosphere