Name: Methocarbamol-[d3]
Brand: BOC Sciences
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General Information

Catalog: BLP-013045

CAS: 1346600-86-9

Molecular Formula: C11H12D3NO5

Molecular Weight: 244.26

Chemical Structure

Description	Methocarbamol-[d3] is the labelled analogue of Methocarbamol, which is a medication used to treat skeletal muscle spasms.
Synonyms	Methocarbamol D3; 3-(2-Methoxyphenoxy)-1,2-propanediol-1-carbamate-d3; 3-(o-Methoxyphenoxy)-2-hydroxypropyl Carbamate-d3; AHR 85-d3; Avetil-d3; Delaxin-d3; Etroflex-d3; Lumirelax-d3; Miolaxene-d3; Neuraxin-d3; Relestrid-d3; Robinax-d3; (±)-Methocarbamol-d3 (methoxy-d3)
IUPAC Name	[2-hydroxy-3-[2-(trideuteriomethoxy)phenoxy]propyl] carbamate
Related CAS	532-03-6 (unlabelled)
Isomeric SMILES	[2H]C([2H])([2H])OC1=CC=CC=C1OCC(COC(=O)N)O
Canonical SMILES	COC1=CC=CC=C1OCC(COC(=O)N)O
InChI	InChI=1S/C11H15NO5/c1-15-9-4-2-3-5-10(9)16-6-8(13)7-17-11(12)14/h2-5,8,13H,6-7H2,1H3,(H2,12,14)/i1D3
InChI Key	GNXFOGHNGIVQEH-FIBGUPNXSA-N
Purity	95% by HPLC; 98% atom D
Solubility	Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Appearance	White to Off-white Solid
Storage	Store at -20°C

Methocarbamol-[d3], a deuterated variant of Methocarbamol, a muscle relaxant utilized in diverse therapeutic and research contexts, offers key applications:

Pharmacokinetic Studies: Delving into pharmacokinetics, Methocarbamol-[d3] becomes a pivotal tool for unraveling the drug’s journey through absorption, distribution, metabolism, and excretion pathways. Its deuterated nature facilitates precise tracking and differentiation within biological systems from the unlabeled drug, enabling optimization of dosing schedules and enhancement of therapeutic outcomes.

Metabolism Research: In the realm of metabolic exploration, Methocarbamol-[d3] aids researchers in delving into the intricate metabolic pathways of the drug and uncovering its metabolites. By harnessing the power of the deuterated isotope, scientists gain nuanced insights into enzyme interactions and metabolic conversions. This knowledge forms the bedrock for evaluating drug safety and understanding potential interactions with other drugs, paving the way for safer pharmaceutical practices.

Drug Interactions: Embarking on a journey of clinical exploration, Methocarbamol-[d3] emerges as a crucial player in studying potential drug interactions. The labeled form enables meticulous tracking of Methocarbamol levels in the presence of concomitant medications, shedding light on any adjustments in drug efficacy and safety profiles. This critical information guides the formulation of appropriate therapeutic regimens, mitigating the risks of adverse effects and ensuring patient well-being.

Analytical Standards: Within the realm of analytical chemistry, Methocarbamol-[d3] assumes a position of trust as an internal standard, particularly in the domain of mass spectrometry. The strategic incorporation of deuterium atoms enables clear differentiation from endogenous and exogenous substances in complex biological matrices, ensuring precise quantification and consistency in analytical outcomes. This fortifies the reliability of bioanalytical assays and enhances the robustness of analytical findings, underpinning the credibility of scientific research and experimentation.