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methyl α-D-glucopyranoside-[3-d]

General Information
Catalog: BLP-007047
Molecular Formula: C7H13DO6
Molecular Weight: 195.19
Chemical Structure
methyl α-D-glucopyranoside-[3-d]
Synonyms methyl alpha-D-[3-2H]glucopyranoside; methyl α-D-[3-D]glucopyranoside
IUPAC Name (2R,3S,4S,5R)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-4-d-3,4,5-triol
Related CAS 97-30-3 (unlabelled)
Solubility Soluble in Methanol, Water
Appearance White to Off-white Solid
Storage Store at -20°C

Methyl α-D-glucopyranoside-[3-d], a deuterated sugar derivative with unique properties, finds applications across various scientific and industrial domains. Here are the key applications:

NMR Spectroscopy: Widely utilized in nuclear magnetic resonance (NMR) spectroscopy, Methyl α-D-glucopyranoside-[3-d] plays a pivotal role in unraveling the intricate structures of carbohydrates. The presence of a deuterium atom within this compound yields a distinctive NMR signal, facilitating in-depth structural scrutiny of sugar molecules. This application is indispensable for deciphering the complex conformations and interactions of carbohydrates at a molecular level.

Metabolic Flux Analysis: In the realm of metabolic investigations, Methyl α-D-glucopyranoside-[3-d] emerges as a key tracer for analyzing metabolic pathways. By integrating this deuterated sugar into metabolic assays, researchers can meticulously monitor its assimilation and transformation within cellular processes. This methodology aids in mapping out metabolic fluxes and comprehending the intricacies of cellular metabolism with precision.

Isotope Labeling Studies: A fundamental reagent for isotope labeling in biochemical research, Methyl α-D-glucopyranoside-[3-d] enables the tracing of biological pathways and mechanisms with a high degree of accuracy. Its incorporation into biomolecules facilitates the monitoring of substrate and product movements in enzymatic studies, offering valuable insights into biochemical processes at a detailed level.

Structural Biology: Delving into sugar-protein interactions, Methyl α-D-glucopyranoside-[3-d] is an essential tool in structural biology investigations. Employed in crystallographic and binding studies, this deuterated glucopyranoside sheds light on the binding sites and affinity of carbohydrate-binding proteins. Such knowledge plays a pivotal role in drug design and enhances our understanding of diseases involving glycoproteins at a molecular level.

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