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Application Area
Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Mitoxantrone-[d8] hydrochloride

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General Information
Catalog: BLP-004772
Molecular Formula: C22H20D8N4O6.HCl
Molecular Weight: 488.99
Chemical Structure
Mitoxantrone-[d8] hydrochloride
Description Mitoxantrone-[d8] hydrochloride is the labelled salt of Mitoxantrone, which is a type II topoisomerase inhibitor. It is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma.
Synonyms Mitoxantrone-D8 hydrochloride
IUPAC Name 1,4-dihydroxy-5,8-bis[2-[(1,1,2,2-tetradeuterio-2-hydroxyethyl)amino]ethylamino]anthracene-9,10-dione;hydrochloride
Related CAS 1179377-27-5 (unlabelled) 70476-82-3 (unlabelled dihydrochloride) 65271-80-9 (unlabelled free base)
Canonical SMILES C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl
InChI InChI=1S/C22H28N4O6.ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;/h1-4,23-30H,5-12H2;1H/i9D2,10D2,11D2,12D2;
InChI Key MKCBCZDNNZPMCG-QPUNNWGTSA-N
Purity ≥98%
Solubility Soluble in Methanol
Storage Store at -20°C
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