Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009911 |
Molecular Formula: C5H8DNO3 |
Molecular Weight: 132.14 |
Chemical Structure |
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Description | N-Acetyl-DL-alanine-[2-d] is a labelled N-Acetyl-DL-alanine. |
Synonyms | DL-Alanine-2-d1, N-Acetyl derivative |
IUPAC Name | 2-acetamido-2-deuteriopropanoic acid |
Related CAS | 1115-69-1 (unlabelled) |
Canonical SMILES | CC(C(=O)O)NC(=O)C |
InChI | InChI=1S/C5H9NO3/c1-3(5(8)9)6-4(2)7/h3H,1-2H3,(H,6,7)(H,8,9)/i3D |
InChI Key | KTHDTJVBEPMMGL-WFVSFCRTSA-N |
Purity | 95% by HPLC; 98% atom D |
N-Acetyl-DL-alanine-[2-d], a deuterated amino acid derivative widely utilized in various scientific and industrial domains, takes center stage in the following key applications, presented with a high degree of perplexity and burstiness:
Stable Isotope Labeling: Delving into the complex world of stable isotope labeling, N-Acetyl-DL-alanine-[2-d] assumes a crucial role in unraveling intricate metabolic pathways within cells. By replacing specific hydrogen atoms with deuterium, researchers embark on a captivating journey to trace the integration and transformation of this compound in metabolic pathways. This endeavor sheds a brilliant light on the convoluted biochemical reactions, unveiling the enigmatic processes through which metabolites undergo mesmerizing transformations within the body.
Structural Biology: In the captivating realm of structural biology, N-Acetyl-DL-alanine-[2-d] emerges as a pivotal protagonist in nuclear magnetic resonance (NMR) spectroscopy studies. The incorporation of deuterium enhances the resolution and sensitivity of NMR signals, empowering scientists to glean intricate insights into protein structures and dynamics. This transformative application is indispensable for decoding the functionality and interplay of biomolecules, illuminating the mesmerizing dance of molecular structures.
Pharmaceutical Development: At the forefront of pharmaceutical innovation, N-Acetyl-DL-alanine-[2-d] plays a critical role in propelling drug development forward by unraveling the mysteries of pharmacokinetics and drug metabolism. Integrating deuterated compounds into drug candidates enables researchers to monitor the absorption, distribution, metabolism, and excretion of drugs within the body. This intelligence is paramount for fine-tuning drug dosages for optimal efficacy and ensuring impeccable safety profiles, reshaping the very fabric of pharmaceutical research.
Chemical Synthesis: In the enthralling world of synthetic chemistry, N-Acetyl-DL-alanine-[2-d] emerges as a versatile gem, serving as a precursor or intermediary in synthesizing deuterated compounds. The introduction of deuterium brings about captivating alterations in the physical and chemical properties of target molecules, influencing their stability and reactivity. This innovative approach empowers chemists to craft specialized compounds tailored for diverse applications, spanning materials science to analytical chemistry, ushering in a captivating new era of chemical ingenuity.
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