N-Acetyl-L-methionine-[d3] is an isotopically labeled compound used in various scientific research applications due to its stable isotope labeling. Here are some key applications of N-Acetyl-L-methionine-[d3]:
Metabolic Tracing: N-Acetyl-L-methionine-[d3] is utilized in metabolic tracing studies to track the metabolic pathways of methionine. Researchers can monitor the incorporation and transformation of the labeled methionine derivative in cellular processes. This helps in elucidating methionine metabolism and its role in various physiological and pathological conditions.
Protein Turnover Studies: In protein turnover studies, N-Acetyl-L-methionine-[d3] is used to measure protein synthesis and degradation rates. By incorporating the labeled methionine into newly synthesized proteins, researchers can quantify protein turnover using mass spectrometry techniques. This is essential for understanding protein dynamics in health and disease.
Quantitative Proteomics: N-Acetyl-L-methionine-[d3] is applied in quantitative proteomics to achieve precise protein quantification. The isotopic labeling allows for differential analysis of protein expression by comparing labeled and unlabeled samples. This approach is valuable in identifying and quantifying proteins in complex biological mixtures, facilitating biomarker discovery and disease diagnosis.
Pharmacokinetics: The labeled compound is also used in pharmacokinetic studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of drugs. By tracking the labeled methionine, scientists can gain insights into the metabolism and bioavailability of methionine-containing drugs. This information is crucial for optimizing drug formulations and therapeutic regimens.
![N-Acetyl-L-methionine-[d3]](https://resource.bocsci.com/structure/n-acetyl-l-methionine-d3-s-methyl-d3.gif)
