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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

N-Ethyl-[d5]-maleimide

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General Information
Catalog: BLP-010022
CAS: 360768-37-2
Molecular Formula: C6H2D5NO2
Molecular Weight: 130.16
Chemical Structure
N-Ethyl-[d5]-maleimide
Description N-Ethyl-[d5]-maleimide is the labelled analogue of N-ethylmaleimide. N-Ethylmaleimide (NEM) is a derivative of maleic acid and is used as a reagent for alkylation and covalent modification of nucleophilic thiol residues on proteins. It acts as an irreversible inhibitor of all cysteine peptidases that alkylates the active site thiol group of the enzymes.
Synonyms N-Ethylmaleimide (Ethyl-D5); 1-Ethyl-1H-pyrrole-2,5-dione-d5; Ethylmaleimide-d5; Maleic Acid N-Ethylimide-d5; NEM-d5; NSC 7638-d5; N-Ethyl Maleimide-d5; NEM (ethyl-d5)
IUPAC Name 1-(1,1,2,2,2-pentadeuterioethyl)pyrrole-2,5-dione
Related CAS 128-53-0 (unlabelled)
Isomeric SMILES [2H]C([2H])([2H])C([2H])([2H])N1C(=O)C=CC1=O
Canonical SMILES CCN1C(=O)C=CC1=O
InChI InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3/i1D3,2D2
InChI Key HDFGOPSGAURCEO-ZBJDZAJPSA-N
Boiling Point 210.0±9.0°C at 760 mmHg
Melting Point 43-46°C (lit.)
Purity 98% by CP; 98% atom D
Density 1.2±0.1 g/cm3
Solubility Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly)
Appearance White to Off-white Low-melting Solid
Storage Store at 2-8°C
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