Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-008513 |
CAS: 1265205-97-7 |
Molecular Formula: C12H3D5F17NO4S |
Molecular Weight: 590.26 |
Chemical Structure |
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Description | N-Ethyl-N-(perfluoro-1-octanesulfonyl) Glycine-[d5] is the isotope labelled analog of N-Ethyl-N-(perfluoro-1-octanesulfonyl) Glycine. N-Ethyl-N-(perfluoro-1-octanesulfonyl) Glycine can be used in biological study for transformation and bioaccumulation of N-Et perfluorooctane sulfonamide ethanol (N-EtFOSE) in soil-earthworm system. |
Synonyms | N-Ethyl-N-[(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)sulfonyl]glycine-d5; 2-(N-Ethylperfluorooctanesulfoamido)acetic Acid-d5; 2-(N-Ethylperfluorooctanesulfonamido)acetic Acid-d5; Et-PFOSA-AcOH-d5; N-Ethyl-N-heptadecylfluorooctane Sulfonyl Glycine-d5; N-Ethylperfluorooctanesulfonamidoacetate-d5 |
Related CAS | 2991-50-6 (unlabelled) |
Melting Point | >130°C(dec.) |
Purity | 98% by CP; 98% atom D |
Solubility | Slightly soluble in DMSO, Methanol |
Appearance | Off-white to Pale Brown Solid |
Storage | Store at -20°C |
N-Ethyl-N-(perfluoro-1-octanesulfonyl) Glycine-[d5] is a deuterated compound commonly used in various scientific applications, particularly as an analytical reagent and in research settings. Here are some key applications of this compound:
Stable Isotope Labeling: The deuterated form of this compound is utilized in mass spectrometry for stable isotope labeling. It helps in enhancing the accuracy and precision of quantitative analysis by differentiating between isotopically labeled and unlabeled molecules. This is critical in metabolomics and proteomics studies, where precise quantification of biological molecules is essential.
Environmental Analytical Chemistry: N-Ethyl-N-(perfluoro-1-octanesulfonyl) Glycine-[d5] can be used as an internal standard in environmental analytical chemistry. Its stable isotopic label makes it ideal for tracking and quantifying perfluorinated compounds in environmental samples. This aids in assessing the impact of these persistent pollutants on ecosystems and human health.
Pharmaceutical Research: In drug metabolism studies, this compound serves as a reference standard due to its robust chemical properties. Its deuterated nature allows for the detailed analysis of drug metabolites and their pathways, providing insights into drug absorption, distribution, metabolism, and excretion (ADME). This information is vital for pharmacokinetics and safety profiling of new drug candidates.
Chemical Synthesis: The compound can be a valuable intermediate or reactant in chemical synthesis, particularly where perfluoroalkyl groups are required. Its usage in synthesis can contribute to the development of new materials with unique properties, such as enhanced stability or specific reactivity. Researchers can utilize this compound to explore novel chemical structures for advanced material applications.
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