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Naloxegol-[13C,d2]

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General Information
Catalog: BLP-004906
Molecular Formula: C33[13C]H51D2NO11
Molecular Weight: 654.79

Chemical Structure

Description	Naloxegol-[13C,d2] is the labelled analogue of Naloxegol, which is a CYP3A4 enzyme inhibitor. It is also a peripherally-selective opioid antagonist. It is used as the treatment of opioid-induced constipation.
Synonyms	Naloxegol 13CD2; (5α,6α)-4,5-Epoxy-6-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propenyl)-morphinan-3,14-diol-13C,d2; Movantik-13C,d2; NKTR 118-13C,d2
IUPAC Name	(4R,4aS,7S,7aR,12bS)-7-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol-13C,d2
Related CAS	854601-70-0 (unlabelled)
Purity	>98%
Solubility	Soluble in DMSO
Storage	Store at -20°C