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(-)-Nebivolol-[d4] Hydrochloride

General Information
Catalog: BLP-000382
Molecular Formula: C22H22D4ClF2NO4
Molecular Weight: 445.92
Chemical Structure
(-)-Nebivolol-[d4] Hydrochloride
Description (-)-Nebivolol-[d4] Hydrochloride, is the labelled analogue of Nebivolol. Nebivolol, a highly selective β1-adrenergic receptor inhibitor, has vasodilatory effect so that could be effective against hypertension. It was just withdrawed a Phase II/III trial for Hypertension in patients with chronic obstructive pulmonary disease.
Synonyms (-)-Nebivolol-d4 Hydrochloride
IUPAC Name (S)-1-((R)-6-fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl-1,1-d2)amino)ethan-2,2-d2-1-ol hydrochloride
Related CAS 920299-33-8 (unlabelled)
Melting Point 198-200°C
Solubility Soluble in DMSO, Methanol
Appearance Off-white Solid
Storage Store at -20°C, under inert atmosphere

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