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Nintedanib-[d8]

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Nintedanib-[d8]

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General Information
Catalog: BLP-005034
CAS: 1624587-87-6
Molecular Formula: C31H25D8N5O4
Molecular Weight: 547.67

Chemical Structure

Description	Nintedanib-[d8] is the labelled analogue of Nintedanib. Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).
Synonyms	Nintedanib D8; Intedanib-d8; (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester-d8; BIBF 1120-d8; Ofev-d8; Vargatef-d8
IUPAC Name	methyl 2-hydroxy-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)acetamido)phenyl)imino)(phenyl)methyl)-1H-indole-6-carboxylate
Related CAS	656247-17-5 (unlabelled)
Solubility	Soluble in DMSO
Appearance	Yellow Solid
Storage	Store at -20°C