Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-005034 |
CAS: 1624587-87-6 |
Molecular Formula: C31H25D8N5O4 |
Molecular Weight: 547.67 |
Chemical Structure |
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Description | Nintedanib-[d8] is the labelled analogue of Nintedanib. Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). |
Synonyms | Nintedanib D8; Intedanib-d8; (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester-d8; BIBF 1120-d8; Ofev-d8; Vargatef-d8 |
IUPAC Name | methyl 2-hydroxy-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)acetamido)phenyl)imino)(phenyl)methyl)-1H-indole-6-carboxylate |
Related CAS | 656247-17-5 (unlabelled) |
Solubility | Soluble in DMSO |
Appearance | Yellow Solid |
Storage | Store at -20°C |
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