Name: O-Desmethyl Mycophenolic Acid Methyl Ester-[d3]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-003640

CAS: 1331670-20-2

Molecular Formula: C17H17D3O6

Molecular Weight: 323.36

Chemical Structure

Description	O-Desmethyl Mycophenolic Acid Methyl Ester-[d3], is the labelled analogue of O-Desmethyl Mycophenolic Acid Methyl Ester, which is a metabolite of Mycophenolic Acid. Mycophenolic acid is an immunosuppressant medication used to prevent rejection following organ transplantation and to treat Crohn's disease.
Synonyms	O-Desmethyl Mycophenolic Acid Methyl Ester D3
IUPAC Name	trideuteriomethyl (E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
Related CAS	33431-38-8 (unlabelled)
Canonical SMILES	CC1=C2COC(=O)C2=C(C(=C1O)CC=C(C)CCC(=O)OC)O
InChI	InChI=1S/C17H20O6/c1-9(5-7-13(18)22-3)4-6-11-15(19)10(2)12-8-23-17(21)14(12)16(11)20/h4,19-20H,5-8H2,1-3H3/b9-4+/i3D3
InChI Key	ONBUUVPMBJOPQE-HZIIEIAOSA-N
Boiling Point	544.1±50.0°C at 760 mmHg
Density	1.3±0.1 g/cm3
Solubility	Soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate, Methanol
Appearance	Pale-Yellow Solid
Storage	Store at-20°C

O-Desmethyl Mycophenolic Acid Methyl Ester-[d3], a deuterated derivative of mycophenolic acid, is a valuable asset in research for tracing drug metabolism and interactions. Here are key applications of O-Desmethyl Mycophenolic Acid Methyl Ester-[d3] presented with high perplexity and burstiness:

Metabolic Studies: This compound plays a pivotal role in metabolic investigations by illuminating the intricate biotransformation pathways of mycophenolic acid. Through meticulous analysis of deuterium-labeled molecules, researchers can precisely discern the metabolic fate of drugs within the body. This knowledge is paramount for fine-tuning therapeutic approaches and unraveling the nuances of drug efficacy.

Pharmacokinetic Research: In the realm of pharmacokinetics, O-Desmethyl Mycophenolic Acid Methyl Ester-[d3] stands as a linchpin for evaluating drug absorption, distribution, metabolism, and excretion. It enables scientists to discriminate between endogenous and labeled metabolites, providing indispensable insights into the drug's clearance kinetics and half-life. Such data are indispensable for ensuring the safe and efficacious utilization of mycophenolic acid in clinical scenarios.

Drug Interaction Analysis: This labeled derivative emerges as a key player in scrutinizing drug interactions, shedding light on the complex interplay between mycophenolic acid and other pharmacological agents. By meticulously tracking the labeled metabolites, researchers can unveil how concurrent medications may impact the drug's metabolic fate.

Toxicological Research: Within the realm of toxicology, O-Desmethyl Mycophenolic Acid Methyl Ester-[d3] assumes a critical role in probing the potential toxicological effects of mycophenolic acid derivatives. Through the strategic use of deuterated counterparts, scientists can monitor metabolic cascades and pinpoint toxic intermediates. This proactive approach aids in predicting plausible adverse outcomes and crafting safer therapeutic agents for the benefit of human health and well-being.