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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

O-Desmethylerlotinib-[13C6] hydrochloride

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General Information
Catalog: BLP-001375
Molecular Formula: C15[13C]6H22ClN3O4
Molecular Weight: 421.83
Chemical Structure
O-Desmethylerlotinib-[13C6] hydrochloride
Description O-Desmethylerlotinib-[13C6] hydrochloride is a labelled hydrochloride of O-Desmethylerlotinib. O-Desmethylerlotinib hydrochloride is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
Synonyms OSI-420-13C6
Related CAS 183320-51-6 (unlabelled)
Purity 98%; 99% atom 13C
Solubility Soluble in Dimethyl sulfoxide
Appearance Light yellow solid
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