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O-Desmethylerlotinib-[13C6] hydrochloride

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General Information
Catalog: BLP-001375
Molecular Formula: C15[13C]6H22ClN3O4
Molecular Weight: 421.83

Chemical Structure

Description	O-Desmethylerlotinib-[13C6] hydrochloride is a labelled hydrochloride of O-Desmethylerlotinib. O-Desmethylerlotinib hydrochloride is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
Synonyms	OSI-420-13C6
Related CAS	183320-51-6 (unlabelled)
Purity	98%; 99% atom 13C
Solubility	Soluble in Dimethyl sulfoxide
Appearance	Light yellow solid