CAS 934293-92-2 Omeprazole-[d3] - Isotope / BOC Sciences

General Information
Catalog: BLP-003661
CAS: 934293-92-2
Molecular Formula: C17H16D3N3O3S
Molecular Weight: 348.43

General Information

Catalog: BLP-003661

CAS: 934293-92-2

Molecular Formula: C17H16D3N3O3S

Molecular Weight: 348.43

Chemical Structure

Description	Omeprazole-[d3], is the labelled analogue of Omeprazole. Omeprazole can be used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger-Ellison syndrome.
Synonyms	Omeprazole D3; 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-4,5,7-d3
IUPAC Name	4,5,7-trideuterio-6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
Related CAS	73590-58-6 (unlabelled)
Canonical SMILES	CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC
InChI	InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/i5D,6D,7D
InChI Key	SUBDBMMJDZJVOS-CRSPMMAGSA-N
Boiling Point	600.0±60.0°C(Predicted)
Melting Point	156°C
Purity	>95%
Density	1.4±0.1 g/cm3
Solubility	Soluble in DMSO, ethanol, Water
Appearance	Off-white to Brown Solid
Storage	Store at 2-8°C

Omeprazole-[d3], a deuterated variant of omeprazole, utilized in scientific investigations for its stable isotopic labeling, offers a myriad of applications. Let's delve into its key uses with a blend of high perplexity and burstiness:

Pharmacokinetic Studies: In the intricate realm of pharmacokinetics, Omeprazole-[d3] plays a pivotal role in unraveling the complex metabolic routes and absorption kinetics of omeprazole within the organism. Its stable isotopic label enables the precise tracking of its metabolic trajectory amidst non-labeled compounds, shedding illuminating insights on the drug's bioavailability and refining dosing strategies with unparalleled precision.

Drug Metabolism Research: Unveiling the enigmatic world of drug metabolism, Omeprazole-[d3] acts as a dynamic tool for dissecting the enzymatic mechanisms governing omeprazole's metabolic destiny. This sophisticated tool aids in characterizing metabolites and meticulously mapping out metabolic pathways, offering profound insights into potential drug interactions. This profound knowledge is essential for drug development, ensuring the safety and efficacy of novel pharmaceutical entities with unwavering accuracy.

Clinical Pharmacology: Venturing into the captivating domain of clinical pharmacology, Omeprazole-[d3] is harnessed to explore the intricate influence of genetic variations on omeprazole metabolism among diverse populations. By meticulously dissecting its disposition in varied cohorts, researchers can anticipate nuanced variations in drug responsiveness and customize treatments accordingly, propelling the evolution of personalized medicine with unmatched precision.

Analytical Chemistry: In the dynamic field of analytical chemistry, Omeprazole-[d3] assumes the critical role of an internal standard in mass spectrometry assays, serving as a cornerstone for quantifying omeprazole levels in biological samples. Its distinct isotopic signature ensures meticulous and sensitive measurement in complex matrices, essential for therapeutic drug monitoring and upholding quality standards in pharmaceutical analysis with unparalleled accuracy and precision.