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Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

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Opaganib-[13C6]

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General Information
Catalog: BLP-000773
Molecular Formula: C17[13C]6H25ClN2O
Molecular Weight: 386.87

Chemical Structure

Description	Opaganib-[13C6] is the labelled analogue of Opaganib. Opaganib is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, Opaganib competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation.
Synonyms	[13C6]-Opaganib
IUPAC Name	3-(4-chlorophenyl-1,2,3,4,5,6-13C6)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide
Related CAS	915385-81-8 (unlabelled)