• Verification code
  • Optimal Prices
    Buying products on this site guarantees the best price
  • Flexible Batches
    Flexible batch size to meet different needs of global customers
  • Prompt Delivery
    Warehouses in multiple cities to ensure timely delivery
  • Quality Assurance
    Strict process parameter control to ensure product quality
  • One-to-one Customization
    One-to-one custom synthesis for special structural needs

Orlistat-[d7]

General Information
Catalog: BLP-003672
Molecular Formula: C29H46D7NO5
Molecular Weight: 502.77
Chemical Structure
Orlistat-[d7]
Description Orlistat-[d7], is the labelled analogue of Orlistat, which is a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase.
Synonyms Orlistat D7
IUPAC Name [(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-4,5,5,5-tetradeuterio-2-formamido-4-(trideuteriomethyl)pentanoate
Related CAS 96829-58-2 (unlabelled)
Canonical SMILES CCCCCCCCCCCC(CC1C(C(=O)O1)CCCCCC)OC(=O)C(CC(C)C)NC=O
InChI InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1/i3D3,4D3,23D
InChI Key AHLBNYSZXLDEJQ-YHFVJDSMSA-N
Purity 97% by CP; 98% atom D
Solubility Soluble in Chloroform, Methanol
Appearance Off-white to Light Tan Solid
Storage Store at-20°C

Orlistat-[d7], a deuterated variant of the anti-obesity drug Orlistat, is primarily utilized in research settings. Here are key applications of Orlistat-[d7] presented with high perplexity and burstiness:

Pharmacokinetic Studies: Orlistat-[d7] plays a pivotal role in pharmacokinetic investigations aimed at unraveling the absorption, distribution, metabolism, and excretion of Orlistat within the human body. Its deuterated structure enables precise tracking and discrimination from endogenous compounds, offering invaluable insights for optimizing dosing strategies and enhancing therapeutic efficacy.

Analytical Chemistry: Acting as an internal standard in mass spectrometry and various analytical techniques, Orlistat-[d7] ensures the accurate quantification of Orlistat levels in biological specimens. Serving as a stable reference, Orlistat-[d7] facilitates precise measurement of the parent drug, essential for developing robust assays for drug monitoring and ensuring stringent quality control in pharmaceutical formulations.

Drug Metabolism Research: Orlistat-[d7] serves as a key tool in elucidating the metabolic pathways of Orlistat, aiding researchers in identifying metabolites and comprehending the drug's biotransformation mechanisms. The insights gleaned from these studies contribute to predicting metabolic interactions and potential side effects, thereby informing the refinement of drug formulations and the mitigation of adverse reactions.

Toxicological Studies: Within the realm of toxicological research, Orlistat-[d7] plays a vital role in evaluating the safety profile and potential toxicities associated with Orlistat usage. By monitoring its fate and effects in preclinical models, researchers can pinpoint any detrimental metabolites or accumulations, supporting the development of safer therapeutic protocols and ensuring adherence to stringent regulatory standards.

Interested in our Service & Products?
Need detailed information?

USA
  • International: 1-631-504-6093
  • US & Canada (Toll free): 1-844-BOC(262)-0123
  • 45-16 Ramsey Road, Shirley, NY 11967, USA
  • Email: info@bocsci.com
  • Fax: 1-631-614-7828
UK
  • 44-20-3286-1088
  • 85 Great Portland Street, London, W1W 7LT
  • Email: info@bocsci.com
Copyright © 2025 BOC Sciences. All Rights Reserved.
0
Inquiry Basket

No data available, please add!

Delete selectedGo to checkout

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy

Accept Cookies
x