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Palmitic acid-[11,11,12,12-d4]

General Information
Catalog: BLP-011511
CAS: 75736-57-1
Molecular Formula: C16H28D4O2
Molecular Weight: 260.45
Chemical Structure
Palmitic acid-[11,11,12,12-d4]
Description Palmitic acid-[11,11,12,12-d4] is the labelled analogue of Palmitic acid. Palmitic acid is a saturated long-chain fatty acid, which is found in fats, milk and meat, and is a major component of palm oil and palm kernel oil. It can be used in the production of soap and cosmetics.
Synonyms Palmitic Acid (11,11,12,12-D4); Hexadecanoic-11,11,12,12-d4 acid; 1-Pentadecanecarboxylic Acid-11,11,12,12-d4; Cetylic Acid-11,11,12,12-d4; NSC 5030-11,11,12,12-d4; Palmitinic Acid-11,11,12,12-d4; Pentadecanecarboxylic Acid-11,11,12,12-d4; n-Hexadecanoic Acid-11,11,12,12-d4
IUPAC Name 11,11,12,12-tetradeuteriohexadecanoic acid
Related CAS 57-10-3 (unlabelled)
Canonical SMILES CCCCCCCCCCCCCCCC(=O)O
InChI InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)/i5D2,6D2
InChI Key IPCSVZSSVZVIGE-NZLXMSDQSA-N
Boiling Point 271.5°C at 133 hPa (100 mmHg)
Melting Point 61-62.5°C
Purity 98%; 98% atom D
Density 0.852 g/cm3 at 25°C
Solubility Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Appearance White Solid
Storage Store at RT

Palmitic acid-[11,11,12,12-d4], a deuterated variant of palmitic acid, emerges as a multifaceted tool in scientific exploration, offering profound insights across various disciplines such as stable isotope tracing, lipidomics, pharmacokinetics, and nutritional research. Here are innovative applications presented with a high degree of perplexity and burstiness:

Stable Isotope Tracing: Positioned as a metabolic beacon, Palmitic acid-[11,11,12,12-d4] stands as a sturdy isotope tracer, delving deep into the intricate realm of lipid metabolism with unparalleled precision. Through meticulous monitoring of the integration of deuterium-laden palmitic acid into the convoluted metabolic pathways, researchers embark on a transformative journey to unveil the enigmatic processes of fatty acid synthesis and oxidation. This meticulous exploration serves as a cornerstone for dissecting lipid metabolism disorders and crafting intricate therapeutic blueprints.

Lipidomics: Introducing the deuterated counterpart of palmitic acid into the realm of lipidomics unveils a treasure trove of insights into the structural complexities of diverse lipid species. Harnessing the sophisticated lens of mass spectrometry, scientists pinpoint and quantify lipids within biological samples with unprecedented accuracy, shedding illuminating light on lipid-related ailments and laying the groundwork for the revelation of novel biomarkers. This nuanced comprehension enriches the intricate tapestry of medical exploration and innovation, paving the way for groundbreaking discoveries.

Pharmacokinetics: Standing as a cornerstone in the sphere of pharmaceutical investigation, Palmitic acid-[11,11,12,12-d4] emerges as a pivotal instrument for unraveling the intricate interplay between drugs and fatty acids. Through meticulous tracing of the in vivo processing of deuterated palmitic acid, researchers illuminate the absorption, distribution, metabolism, and excretion (ADME) of associated therapeutic agents. This wealth of insights streamlines the optimization of drug formulations and delivery mechanisms, amplifying the effectiveness of pharmaceutical interventions and shaping the trajectory of medical treatment.

Nutritional Research: Spearheading the forefront of dietary inquiries, Palmitic acid-[11,11,12,12-d4] illuminates the impact of saturated fats on human health in novel ways. By incorporating this uniquely labeled acid into dietary studies, researchers unravel the intricate mechanisms through which dietary palmitic acid influences lipid profiles and metabolic well-being over time. This groundbreaking research endeavor fortifies the development of tailored dietary protocols and interventions aimed at combatting metabolic disorders, heralding a transformative era in nutritional science and well-being.

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