PB-22 4-Hydroxypentyl metabolite-[d5] - Isotope / BOC Sciences

General Information
Catalog: BLP-009094
Molecular Formula: C23H17D5N2O3
Molecular Weight: 379.46

General Information

Catalog: BLP-009094

Molecular Formula: C23H17D5N2O3

Molecular Weight: 379.46

Chemical Structure

Description	PB-22 4-Hydroxypentyl metabolite-[d5] is the labelled derivative of PB-22 4-Hydroxypentyl metabolite, a stable-labelled internal standard of PB-22 4-Hydroxypentyl metabolite, also known as the Omega minus one-OH metabolite of PB-22. The 4-Hydroxypentyl analog is the major urinary metabolite of PB-22, a synthetic analog of JWH-018.
Synonyms	PB-22 4-Hydroxypentyl metabolite-D5 (indole-D5); quinolin-8-yl 1-(4-hydroxypentyl)-1H-indole-3-carboxylate-d5
IUPAC Name	quinolin-8-yl 2,4,5,6,7-pentadeuterio-1-(4-hydroxypentyl)indole-3-carboxylate
Canonical SMILES	CC(CCCN1C=C(C2=CC=CC=C21)C(=O)OC3=CC=CC4=C3N=CC=C4)O
InChI	InChI=1S/C23H22N2O3/c1-16(26)7-6-14-25-15-19(18-10-2-3-11-20(18)25)23(27)28-21-12-4-8-17-9-5-13-24-22(17)21/h2-5,8-13,15-16,26H,6-7,14H2,1H3/i2D,3D,10D,11D,15D
InChI Key	USLCLHHNJHEBGL-DVHJCUEESA-N
Purity	98% by CP; 98% atom D

PB-22 4-Hydroxypentyl metabolite-[d5] is a deuterated analog of a synthetic cannabinoid metabolite and it finds several important applications in bioscience research and forensic analysis. Here are some key applications of PB-22 4-Hydroxypentyl metabolite-[d5]:

Analytical Standards: PB-22 4-Hydroxypentyl metabolite-[d5] is used as a stable isotope-labeled internal standard in mass spectrometry assays. It aids in the quantification and accurate detection of PB-22 metabolites in biological samples. Researchers and forensic analysts utilize this compound to ensure precise and reliable measurement of drug metabolites.

Forensic Toxicology: This compound is instrumental in forensic toxicology for confirming the presence of synthetic cannabinoids in biological specimens such as blood or urine. By comparing the deuterated metabolite with the native metabolite, laboratories can differentiate between drug use and contamination. This distinction is crucial for legal and clinical investigations involving synthetic cannabinoid usage.

Pharmacokinetics Studies: PB-22 4-Hydroxypentyl metabolite-[d5] can be used in pharmacokinetic studies to track the metabolic pathways of PB-22 in the body. By monitoring the deuterated metabolite over time, researchers gain insights into the drug’s absorption, distribution, metabolism, and excretion (ADME). This information is essential for understanding the drug’s behavior and potential impacts on health.

Biological Research: In cellular and molecular biology, this deuterated metabolite can be used to study the biological effects of PB-22 and its metabolites on cellular processes. By examining the interactions of labeled and unlabeled metabolites, scientists can explore receptor binding, signal transduction, and biochemical pathways influenced by synthetic cannabinoids. This knowledge contributes to a deeper understanding of cannabinoid pharmacology and toxicity.