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* Service & Products of Interested: [Isotope Labeled Inhibitors] PD-173074-[d9] (1794979-29-5)
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PD-173074-[d9]

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General Information
Catalog: BLP-012509
CAS: 1794979-29-5
Molecular Formula: C28H32D9N7O3
Molecular Weight: 532.73

Chemical Structure

Description	Labelled PD 173074, a selective FGFR1 and FGFR3 inhibitor. The compound induced a dose-dependent reduce in cell viability and an increase in apoptosis, accompanied by a decrease in extracellular signal-related kinase phosphorylation.
Synonyms	PD-173074 D9; N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl-d9)urea
IUPAC Name	1-[2-[4-(diethylamino)butylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]urea
Related CAS	219580-11-7 (unlabelled)
Canonical SMILES	CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
InChI	InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36)/i3D3,4D3,5D3
InChI Key	DXCUKNQANPLTEJ-YJMGCJIZSA-N
Melting Point	83-85°C
Density	1.2±0.1 g/cm3
Solubility	Soluble in Chloroform, Methanol
Appearance	Yellow Solid
Storage	Store at -20°C

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