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Pemetrexed-[13C5]

General Information
Catalog: BLP-000914
Molecular Formula: C15[13C]5H21N5O6
Molecular Weight: 432.37
Chemical Structure
Pemetrexed-[13C5]
Description Pemetrexed-[13C5] is the labelled analogue of Pemetrexed. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis.
Synonyms [13C5]-Pemetrexed
IUPAC Name (4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic-13C5 acid
Related CAS 137281-23-3 (unlabelled)
Appearance Light Green Solid

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