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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Picropodophyllotoxin-[d3]

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General Information
Catalog: BLP-003811
CAS: 1454782-81-0
Molecular Formula: C22H19D3O8
Molecular Weight: 417.42
Chemical Structure
Picropodophyllotoxin-[d3]
Description Picropodophyllotoxin-[d3], is the labelled analogue of Picropodophyllotoxin. Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT).
Synonyms Picropodophyllin-d3; Picropodophyllotoxin D3
IUPAC Name (5R,5aR,8aS,9R)-9-[3,5-dimethoxy-4-(trideuteriomethoxy)phenyl]-5-hydroxy-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Related CAS 477-47-4 (unlabelled)
Canonical SMILES COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
InChI InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19+,20-/m0/s1/i3D3
InChI Key YJGVMLPVUAXIQN-IWIYTUSESA-N
Boiling Point 597.9±50.0°C at 760 mmHg
Melting Point 201-207°C
Purity 97% by CP; 98% atom D
Density 1.4±0.1 g/cm3
Solubility Soluble in Chloroform
Appearance White Solid
Storage Store at-20°C, Under inert atmosphere
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