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R-Doxazosin-[13C4]

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General Information
Catalog: BLP-000888
Molecular Formula: C19[13C]4H25N5O5
Molecular Weight: 455.45

Chemical Structure

Description	R-Doxazosin-[13C4] is the labelled analogue of R-Doxazosin, which is an impurity of Doxazosin. Doxazosin is a quinazoline-derivative and long-lasting α1 adrenergic receptor blocker. It inhibits the binding of norepinephrine, which is released from sympathetic nerve terminals, to the α-1 receptors on the membrane of vascular smooth muscle cells. It is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms. It may have an inhibitory effect on cholesterol synthesis independent of the LDL receptor.
Synonyms	[13C4]-R-Doxazosin
IUPAC Name	(R)-(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl-2,3,5,6-13C4)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone
Related CAS	70918-17-1 (unlabelled)