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(R)-Verapamil-[d7] hydrochloride

General Information
Catalog: BLP-013660
Molecular Formula: C27H32D7ClN2O4
Molecular Weight: 498.11
Chemical Structure
(R)-Verapamil-[d7] hydrochloride
Description (R)-Verapamil-[d7] hydrochloride is the labelled analogue of (R)-Verapamil hydrochloride, which is an inhibitor of the p-glycoprotein efflux pump in multidrug resistant tumor cells.
Synonyms (R)-Verapamil D7 hydrochloride; (αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile-d7 Hydrochloride; Dexverapamil-d7 Hydrochloride; NSC 632821-d7; (R)-(+)-Verapamil D7 hydrochloride
IUPAC Name (2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(1,1,1,2,3,3,3-heptadeuteriopropan-2-yl)pentanenitrile;hydrochloride
Related CAS 38176-02-2 (unlabelled) 38321-02-7 (unlabelled free base)
Canonical SMILES CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
InChI InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H/t27-;/m1./s1/i1D3,2D3,20D;
InChI Key DOQPXTMNIUCOSY-KMPOVETJSA-N
Solubility Soluble in Methanol, Water
Appearance Off-white Solid
Storage Store at 2-8°C

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