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* Service & Products of Interested: [Isotope Labeled Inhibitors] rac-Ruxolitinib-[d8] (1794791-38-0)
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rac-Ruxolitinib-[d8]

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General Information
Catalog: BLP-004086
CAS: 1794791-38-0
Molecular Formula: C17H10D8N6
Molecular Weight: 314.41

Chemical Structure

Description	Rac-Ruxolitinib-[d8] is the labelled analogue of Ruxolitinib. Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
Synonyms	β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile-d8
IUPAC Name	3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Related CAS	941688-05-7 (unlabelled)
Canonical SMILES	C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChI	InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/i1D2,2D2,3D2,4D2
InChI Key	HFNKQEVNSGCOJV-SVYQBANQSA-N
Melting Point	>100°C
Purity	>98%
Solubility	Soluble in Ethyl Acetate, Methanol
Appearance	White to Off-white Solid
Storage	Store at-20°C, Under inert atmosphere