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Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

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Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

rac-Ruxolitinib-[d8]

Name: rac-Ruxolitinib-[d8]
Brand: BOC Sciences
Rating: 5 (1 reviews)

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General Information
Catalog: BLP-004086
CAS: 1794791-38-0
Molecular Formula: C17H10D8N6
Molecular Weight: 314.41

Chemical Structure

Description	Rac-Ruxolitinib-[d8] is the labelled analogue of Ruxolitinib. Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
Synonyms	β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile-d8
IUPAC Name	3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Related CAS	941688-05-7 (unlabelled)
Canonical SMILES	C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChI	InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/i1D2,2D2,3D2,4D2
InChI Key	HFNKQEVNSGCOJV-SVYQBANQSA-N
Melting Point	>100°C
Purity	>98%
Solubility	Soluble in Ethyl Acetate, Methanol
Appearance	White to Off-white Solid
Storage	Store at-20°C, Under inert atmosphere