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Regorafenib-[13C,d3] N-Oxide

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General Information
Catalog: BLP-005983
Molecular Formula: C20[13C]H12D3ClF4N4O4
Molecular Weight: 502.83

Chemical Structure

Description	An isotope labelled metabolite of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.
Synonyms	4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-2-[(13C,D3)methylcarbamoyl]pyridin-1-ium-1-olate
Related CAS	835621-11-9 (unlabelled)
Purity	95% by HPLC; 98% atom D; 98% atom 13C
Appearance	White Powder