| Description |
Labelled Remdesivir. Remdesivir, an analog nucleotide inhibitor, with effectively antiviral activity in vitro against various virus, including Ebola virus, Marburg virus, HCoV-NL63, HCoV-OC43, HCoV-229E, Mouse hepatitis virus (MHV), SARS-CoV, MERS-CoV and related bat coronavirus, HKU5, and PDCoV (porcine delta-coronavirus). Remdesivir is also reported to have potential antiviral activity against COVID-19. |
| Synonyms |
Remdesivir-d5; 2-Ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy-d5)phosphoryl)-L-alaninate; 2-Ethylbutyl N-[(S)-[2-C-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitril-6-O-yl](phenoxy-d5)phosphoryl]-L-alaninate; Covifor-d5; GS 5734-d5; Remdesivir-[d5] (Mixture of diastereomers); Remdesivir-d5 (Mixture of diastereomers); N-[(S)-Hydroxy(phen-2,3,4,5,6-d5)oxyphosphinyl]-L-alanine, 2-ethylbutyl ester, 6-ester with 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile |
| IUPAC Name |
2-ethylbutyl (2S)-2-[[(S)-[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-(2,3,4,5,6-pentadeuteriophenoxy)phosphoryl]amino]propanoate |
| Related CAS |
1809249-37-3 (unlabelled)
|
| Canonical SMILES |
CCC(CC)COC(=O)C(C)NP(=O)(OCC1C(C(C(O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4 |
| InChI |
InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1/i6D,7D,8D,9D,10D |
| InChI Key |
RWWYLEGWBNMMLJ-ZOXPTPMHSA-N |
| Purity |
≥95%; 98% atom D |
| Density |
1.473±0.14 g/cm3 |
| Solubility |
Soluble in DMF, DMSO, Methanol |
| Appearance |
White crystalline solid |
| Storage |
Store at 2-8 °C |
![Remdesivir-[d5]](https://resource.bocsci.com/structure/2440242-47-5.gif)
