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Rociletinib-[d8]

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General Information
Catalog: BLP-004151
Molecular Formula: C27H20D8F3N7O3
Molecular Weight: 563.61

Chemical Structure

Description	A labelled form of Rociletinib. Rociletinib is a third-generation irreversible kinase inhibitor of epidermal growth factor receptor (EGFR). Rociletinib was shown to inhibit the proliferation of non-small cell lung cancer (NSCLC) cells expressing mutant EGFR. It also exhibits anti-tumor activity in NSCLC EGFR mutant xenograft models.
Synonyms	N-(3-{[2-({4-[4-acetyl(D8)piperazin-1-yl]-2-methoxyphenyl}amino)-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide; N-[3-[[2-[4-(4-Acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide-d8; CO-1686-d8
Related CAS	1374640-70-6 (unlabelled)
Purity	>98%