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(S)-(+)-1,2-Propanediol-1-[13C]

General Information
Catalog: BLP-005542
Molecular Formula: CH3CH(OH)[13C]H2OH
Molecular Weight: 77.09
Chemical Structure
(S)-(+)-1,2-Propanediol-1-[13C]
Description (S)-(+)-1,2-Propanediol-1-[13C], a labelled analogue of (S)-(+)-1,2-Propanediol, can be used in the analysis of endogenous metabolite. Bearing a chiral center in the molecule, (S)-(+)-1,2-Propanediol-1-13C can be also served as a useful building block in the synthesis of chiral bio-active compounds.
IUPAC Name (2S)-(1-13C)propane-1,2-diol
Related CAS 4254-15-3 (unlabelled)
Canonical SMILES CC(CO)O
InChI InChI=1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3/t3-/m0/s1/i2+1
InChI Key DNIAPMSPPWPWGF-QQPKUSCQSA-N
Boiling Point 186-188°C at 765 mmHg
Purity 96% by CP; ≥99% atom 13C
Density 1.049 g/mL at 20°C
Appearance Liquid

(S)-(+)-1,2-Propanediol-1-[13C] an isotopically labeled compound plays a vital role in various scientific research and industrial applications. Here are key applications presented with high perplexity and burstiness:

Metabolic Flux Analysis: In the realm of metabolic research, isotopically labeled compounds like (S)-(+)-1,2-Propanediol-1-[13C] serve as invaluable tools for tracing metabolic pathways and quantifying metabolic fluxes within living organisms. By integrating this compound into metabolic studies, scientists can meticulously track the carbon flow through diverse metabolic pathways using nuclear magnetic resonance (NMR) or mass spectrometry techniques. This in-depth analysis facilitates a profound understanding of metabolic processes and the intricate regulation of metabolic networks operating within cells.

Pharmaceutical Development: (S)-(+)-1,2-Propanediol-1-[13C] finds application in synthesizing isotopically labeled pharmaceutical compounds essential for conducting pharmacokinetic investigations. These labeled drugs play a crucial role in unraveling absorption, distribution, metabolism, and excretion profiles necessary for optimizing dosing regimens and elucidating drug pathways. By leveraging (S)-(+)-1,2-Propanediol-1-[13C], researchers can advance pharmaceutical development and enhance the efficacy of therapeutic interventions through a comprehensive understanding of drug behavior in biological systems.

NMR Spectroscopy Studies: Within the domain of analytical chemistry, (S)-(+)-1,2-Propanediol-1-[13C] functions as a versatile probe in NMR spectroscopy, enabling the detailed study of molecular structures and dynamic behaviors. The 13C labeling enhances the resolution and sensitivity of spectra, empowering researchers to glean insights into molecular conformation and interactions. This application is particularly valuable for investigating complex biological molecules and mixtures, shedding light on intricate molecular dynamics and structural properties through advanced spectroscopic analysis.

Biochemical Pathway Engineering: Leveraging the isotopic labeling offered by (S)-(+)-1,2-Propanediol-1-[13C], researchers engage in the sophisticated task of engineering biochemical pathways, especially in the domains of synthetic biology and biochemical engineering. By incorporating labeled intermediates into pathways, scientists can monitor and optimize the carbon flow within engineered metabolic networks. This strategic approach facilitates the design of highly efficient microbial strains tailored for synthesizing biofuels, pharmaceuticals, and biochemicals, thus driving innovation in sustainable bioproduction processes.

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