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(S)-Cystathionine-[d4]

General Information
Catalog: BLP-013983
Molecular Formula: C7H10D4N2O4S
Molecular Weight: 226.28
Chemical Structure
(S)-Cystathionine-[d4]
Synonyms (S)-Cystathionine-d4; Allocystathionine-d4; (2S)-2-amino-4-(2-amino-2-carboxyethyl)sulfanylbutanoic acid-d4; (2S)-2-Amino-4-((2-amino-2-carboxyethyl)thio)butanoic acid-d4; S-[(2-RS)-2-Amino-2-carboxyethyl)-L-homocysteine-3,3,4,4-d4
IUPAC Name (2S)-2-amino-4-(2-amino-2-carboxyethyl)sulfanyl-3,3,4,4-tetradeuteriobutanoic acid
Related CAS 61949-06-2 (unlabelled) 535-34-2 (unlabelled DL-isomer)
Purity 95% by HPLC; 98% atom D
Solubility Soluble in Aqueous Acid (Slightly), Water (Slightly, Sonicated)
Storage Store at -20°C under inert atmosphere

(S)-Cystathionine-[d4], a deuterium-labeled variant of the amino acid cystathionine, is frequently utilized as an internal standard in various research contexts. Here are the key applications:

Metabolomics Research: Delving into metabolomics, researchers often employ (S)-Cystathionine-[d4] to quantify cystathionine levels in biological samples through mass spectrometry. The deuterium labeling enables precise differentiation from endogenous cystathionine during analysis, facilitating insights into metabolic pathways and disease states associated with cystathionine metabolism.

Pharmacokinetic Studies: In pharmacokinetic investigations, researchers utilize (S)-Cystathionine-[d4] to monitor and measure the absorption, distribution, metabolism, and excretion (ADME) of cystathionine in biological systems. The stable isotope labeling provides accurate tracing without disrupting normal metabolic processes. This data is essential for drug development and comprehending biological responses to compounds.

Nutritional Studies: (S)-Cystathionine-[d4] is integrated into nutritional studies to explore how diet influences cystathionine metabolism. By incorporating the labeled compound into dietary interventions, researchers can track changes in cystathionine levels and metabolism. This investigation sheds light on the role of cystathionine in nutrition and its implications for health outcomes.

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